BloodSTOP iX sterile resorbable hemostat

Description

 

 

Hemostasis is always crucial

BloodSTOP® iX Advanced Hemostat with WoundHEAL® is a clinically proven, research-based hemostatic dressing and wound healing matrix that provides rapid hemorrhage control, dramatically reducing blood loss. It is an all-natural, plant-based, biocompatible, water-soluble, etherified carboxymethyl cellulose (ECMC) matrix that utilizes patented technology to achieve superior hemostasis and fast wound healing.
Well-established as an ideal hemostatic dressing, BloodSTOP® iX has demonstrated in an animal model the ability to modulate endogenous tissue cytokines, as well as to bind to cellular receptors on cell membranes and thereby activating Wnt/Frizzled cellular signaling (1). This leads to the activation of endogenous stem cells and cytokines, which brings about angiogenesis and tissue regeneration.
Additionally, it has shown to decrease inflammatory cytokines, thereby reducing the infection and inflammation risk, and promoting fast wound healing (1,2).

BloodSTOP® iX has European Union CE Class III absorbable implant certification and is for use with anticoagulant medications (blood thinners).

Producer: LifeScience PLUS Inc. (USA)

Features ⇒ Benefits

• Provides rapid hemostasis under a minute³ (from minor to larger wounds) ⇒ Dramatically reduces blood loss.
• Matrix turns into an adhesive gel upon contact with blood and exudates ⇒ Creates a moist wound environment that assists with natural granulation and epithelialization and promotes wound healing and proliferation of tissue growth.
• The gel sticks, seals, and protects the wound without any blood oozing³ ⇒ Prevents contamination, and reduces the risk of infection and inflammation.
• The sticky gel provides long-lasting and stable hemostasis ⇒ No rebleeding and adhesion upon removal of secondary dressing coverage.^4,5,6
• Forms translucent gel seal ⇒ Allows easy monitoring of wounds without disrupting blood clotting.
• pH neutral: ~7.2, natural plant-based, nontoxic, no irritation, nonexothermic ⇒ Will not irritate the wound, and reduces pain upon application and removal.
• 100% absorbable, biocompatible, and biodegradable; can be used on patients with blood thinner medications (EU)^4,5  ⇒ Leaves no residue in the wound; no reported adverse patient events.
• Stabilizes wounds with fewer materials than typically needed with other products ⇒ Time and cost-effective treatment.
• Easy to remove with sterile water or saline ⇒ Softens, loosens and removes slough and necrotic debris from the wound bed.
• Gel matrix provides flexibility ⇒ Conforms to any wound: small, large, irregular, acute, chronic, surgical, or trauma injury.
• Sealed in sterile, lightweight, waterproof packaging ⇒ Easy to carry anywhere.

1 Peng D, B. Reed-Maldonado A, Banie L, Wang G, Lin G, F. Lue T. Carboxymethylcellulose Activates Dermal Cells and Adipose-Derived Stem Cells Through Wnt/β-catenin Pathway. J Surg Res (Houst). 2021;04(01). doi:10.26502/jsr.10020117

2 Ju S, Wang K, Qiao L et al. Application of BloodSTOP iX Wound Heal Nanocellulose Matrix for Burn Wound Care. J Surg Res (Houst). 2021;04(01). doi:10.26502/jsr.10020105

3 Ethox International, Rush, NY, Hemostasis Assessment of BloodSTOP, BloodSTOP iX, GLP-2006-0332, 2006.

4 Ferretti L, Qiu X, Villalta J, Lin G. Efficacy of BloodSTOP iX, Surgicel, and Gelfoam in Rat Models of Active Bleeding From Partial Nephrectomy and Aortic Needle Injury. Urology. 2012;80(5):1161.e1-1161.e6. doi:10.1016/j.urology.2012.06.048

5 BloodSTOP iX has European Union CE Class III absorbable implant certification, and for use with anticoagulant medications (blood thinners). BloodSTOP iX currently has US FDA 510(k) clearance for topical wound hemostasis.

6 Li H, Wang L, Alwaal A et al. Comparison of Topical Hemostatic Agents in a Swine Model of Extremity Arterial Hemorrhage: BloodSTOP iX Battle Matrix vs. QuikClot Combat Gauze. Int J Mol Sci. 2016;17(4):545. doi:10.3390/ijms17040545